Extended-spectrum beta-lactamases (ESBL) are enzymes that confer resistance to most beta-lactam antibiotics, including penicillins, cephalosporins, and the monobactam aztreonam. Infections with ESBL-producing organisms have been associated with poor outcomes.
Community-acquired ESBL producing Enterobacteriaceae are prevalent worldwide [1]. Reliably identification of ESBL-producing organisms in clinical laboratories is difficult, so their prevalence is likely underestimated. Carbapenems are the best antimicrobial agent for infections caused by such organisms.... Authorized only
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