Gout is a common disease both in primary care and hospital practice. In UK general practices gout has an overall prevalence of 1.39%, with a male:female ratio of 3.6:1, but the disease remains rare in pre-menopausal women [1]. The incidence and prevalence of gout are both strongly age-related with a prevalence >7% in men, and >4% in women, over the age of 75 years [1].
Clinical manifestations of gout are associated with monosodium urate (MSU) crystal deposition in articular or peri-articular tissues and in the renal tract. It can present, and in some cases progress through four clinical stages if left untreated: asymptomatic hyperuricaemia, acute gout, intercritical or interval gout and chronic tophaceous gout. Classification criteria were proposed in 1977 and the presence of six or more of these criteria makes a diagnosis of gout highly likely [2] although the gold standard for diagnosis is the demonstration of urate crystals in synovial fluid or in a tophus by polarized light microscopy. ...Authorized only
Gout British Society for Rheumatology and British Health Professionals in Rheumatology Guideline for the Management of Gout, 2007 Rheumatology, Summary
Clinical manifestations of gout are associated with monosodium urate (MSU) crystal deposition in articular or peri-articular tissues and in the renal tract. It can present, and in some cases progress through four clinical stages if left untreated: asymptomatic hyperuricaemia, acute gout, intercritical or interval gout and chronic tophaceous gout. Classification criteria were proposed in 1977 and the presence of six or more of these criteria makes a diagnosis of gout highly likely [2] although the gold standard for diagnosis is the demonstration of urate crystals in synovial fluid or in a tophus by polarized light microscopy. ...Authorized only
Gout British Society for Rheumatology and British Health Professionals in Rheumatology Guideline for the Management of Gout, 2007 Rheumatology, Summary
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